Clinical Topics - Nephrology Education & Case Studies | NephroApp

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Scleroderma Renal Crisis: ACE Inhibitor First, Steroids Out

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Scleroderma Renal Crisis (SRC) is a life-threatening complication of systemic sclerosis (SSc), classically presenting wi...

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Nov 09, 2025

Hypokalaemia With Normal-Anion-Gap Acidosis: RTA vs Diarrhoea

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Hypokalemia with metabolic acidosis is a challenging clinical scenario that requires a systematic approach to uncover th...

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Oct 13, 2025

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12 case scenarios available

AKI in Rheumatoid Arthritis: Hidden Methotrexate Toxicity and Bilateral Kidney Stones

Exam · Acute Kidney Injury

A woman with rheumatoid arthritis on hydroxychloroquine (Plaquenil) is referred with AKI, creatinine 200 µmol/L. I start...

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4 days ago

Lupus Nephritis: Planning Pregnancy and the Proteinuria Rise After MMF to Azathioprine

Exam · Special Topics

A woman with class III lupus nephritis in remission for 5 years (normal kidney function, proteinuria 400 mg/day) wants t...

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4 days ago

Kidney Transplant Recipient Evaluation (Initial Work-up and Candidacy)

Exam · Transplant

The aim of the evaluation is to decide, through a multidisciplinary team (transplant physician, transplant surgeon and a...

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1 week ago

Weight Loss in CKD Stage 5 Before Dialysis: Work-up and Management

Exam · CKD & Bone-Mineral

Weight loss in a CKD 5 patient who is not on dialysis is protein-energy wasting (PEW) until proven otherwise, but unexpl...

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1 week ago

Post-Transplant Lymphoproliferative Disorder (PTLD)

Exam · Transplant

PTLD is a spectrum of lymphoid proliferation, from reactive polyclonal lesions to frank lymphoma, caused by reduced T-ce...

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1 week ago

Peritoneal Equilibration Test: Standard vs Modified PET

Exam · Peritoneal Dialysis

Always name the PET variant before describing a protocol or interpreting a number. Here, standard (classic) PET means a...

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1 week ago

Early Kidney Transplant Complications and Management of Urine Leak

Exam · Transplant

Early after kidney transplant, graft dysfunction or a perigraft collection is surgical until proven otherwise. The exami...

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1 week ago

Suspected Transplant Rejection When No Biopsy Is Available

Exam · Transplant

The gold standard for diagnosing rejection is a transplant biopsy with donor-specific antibody (DSA) testing; no non-inv...

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1 week ago

PD Haemoperitoneum (Bloody Effluent)

Exam · Peritoneal Dialysis

Bloody PD effluent looks alarming but is rarely serious. The examiner wants a stepwise answer: confirm the patient is st...

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1 week ago

Statins in Haemodialysis Patients: The Evidence (4D, AURORA, SHARP, KDIGO)

Exam · Hemodialysis & Access

The examiner asks: do we use statins in haemodialysis patients, and what is the evidence? The one-line answer is do not...

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1 week ago

Tunnelled Haemodialysis Catheter Infection and CRBSI

Exam · Hemodialysis & Access

A tunnelled dialysis catheter (permicath) infection is one of three things: an exit-site infection (cellulitis within 1-...

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1 week ago

Dialysis-Related Amyloidosis (Abeta2M)

Exam · Hemodialysis & Access

Dialysis-related amyloidosis (Aβ2M) is amyloid derived from β2-microglobulin (11.8 kDa, the light chain of HLA...

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1 week ago